My computer loads SW:KOTOR 2 just fine and it's Windows 7 Ultimate. Or load the config screen in KOTOR 2 launcher.
Try to load it with the 'Windows XP Compatibility'
is Windows 10, I'm not sure of my hardware (though I know it can run the game, as it did prior to the Windows 10 update) And I'm using the disc from the Knights of the Old Republic Complete Collection (The 2-dicspack that comes with KOTOR 1 and KOTOR 2).